Know more about the saizen hormone from its official site!!!

The human growth hormone is manufactured by the pituitary gland in the brain and is responsible for the development of children and adults. The individuals can go through the deficiency of this hormone, as a result of any accident, injury, genetic or hereditary problem, etc. This deficiency may lead to improper functioning of the pituitary gland. IN order to overcome this deficiency, the individuals can start intake of the HGH supplement.

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There are several brands manufacturing the HGH supplement. The Saizen hormone is one such brand manufacturing the growth hormone supplements. The individuals can get detailed information about the saizen hormone from its official site, i.e. These supplements are recommended by the doctors, in case the body does not produce adequate levels of growth hormone. The saizen hormone is a synthetic drug manufactured in the laboratories.

The synthetic growth hormones help the growth hormones in mimicking the number of the growth hormones produced by the body along with their chemical construction. The only difference between the real growth hormones and the synthetic growth hormones is that the real growth hormones are produced inside the body and are endogenous in nature, whereas the synthetic growth hormones are manufactured outside the body and are called exogenous in nature.

The pituitary gland is responsible for maintenance and functioning of several other brands that make up the endocrine system. The pituitary gland also has to send or receive directions from the hypothalamus gland, before sending out instructions for increasing or decreasing the production and secretion of hormones. The pituitary gland sends the instructions with the help of a messenger known as the growth hormone releasing hormone. The increase or decrease of the growth hormone depends on the age of an individual. So, after a certain age, it begins to decline. If this level of hormones drops very low, in such cases the doctors recommend the HGH injections.

Saizen is the most common hormone drug available in the market today. This drug is also a prescription only drug, which is meant for the treatment of individuals based on specific criteria. Some other brands of growth hormone include the Serostim, Serono, etc. The treatment of adults using the growth hormone provides them numerous benefits. Some of its benefits are listed below:

  • Decreased body fat mass
  • Increased density of bones
  • Increased exercise or activity capacity
  • Increased muscle mass

The problems caused by the deficiencies of the growth hormones are not that common. The saizen growth hormone injection is generally prescribed to the pediatric patients, who are diagnosed with growth failure occurring as a result of the secretion of the growth hormone. The dosage of the supplement depends on the severity of the deficiency. The dosage for the adults is based on weight as well as on other contributing factors including the age, diagnosis, etc.The side effects on intake of the saizen hormone are also mild, but still careful sight of a physician is also recommended.

The individuals can collect more information about saizen from the website link, i.e.

Know the boundaries in order to avoid the side effects

There are hundreds of myths regarding the use of medicine and at some point, such myths are even true. But, in such myths also there is some limitation and precaution which people some time ignores or avoid. Thus, such negligence often leads to nowhere, but to increase the chances of side effects which would affect the internal organ of the body. There is a similar kind of trends in the steroids sector also where there are myths that it increases the body endurance and stamina along with pump up the muscles in order to have more glossy body development. It is true that steroids enhance the body development, but to some extent, it is also limited which means that the excessive dosages of steroids may lead to some serious side effects which affect the working of some important organ part of the body. Similarly, Clenbuterol which is a thermogenic steroid goes through the same theory of myths and exception. But, if one knows how much clenbuterol is safe, then all the threads and side effects associated with the steroids are solved.

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There are a number of people around the world who consume steroids for burning the extra fats and having a perfect slim and tonned body, whereas the professional bodybuilders and athletes consume clencycle to enhance the body development and its growth along with improving the stamina and endurance so that it could help them during their intense workout. It is also used to stack with some other steroids in order to cut the cycle and increase the effectiveness of the steroids.

But, there is some limitation of stacking which means that it cannot be stack with every steroid for the effective result, in common it is widely used to stack with testosterone and Winstrol. As, it is controlled drug there are some side effects which at a certain point of time(first user) its impact is minimal, but the degree of side effects increases as the time passes by when there is no increase in the body temperature (old user), at that point of time the users must stop taking Clenbuterol  solely. The users can either use some improved drugs or they can stack with other steroids. The normal cycle of the Clenbuterol  4-6 weeks, in order to check it see if the body temperature has returned to normal. In order to have risk free having of steroids, it is advisable that people must know how much clenbuterol is safe.

One must know that consuming of dosages varies from one person to another. Men generally can take 2-8 tablets per day while women must take 2-4 tablets per day. This is advisable that if clenbuterol is taken excessively for too long period of time without any precaution, it will be unsafe to use because it may increase the of high blood pressure or heart problems. If one have a bad reaction such as jitter or anxiety whenever you touch a cup of hot coffee or caffeine then they must stop consuming clenbuterol. Apart from this if one follow guidelines and take aforementioned dosages of Clenbuterol it is considered as the most efficient drug to burn the fat and to have a perfect tonned body.

Cendana Capital — which funds 15 top seed-stage groups — just raised a ton of capital

Seven years ago, when he first approached investors with the idea of creating a fund-of-funds that would invest in seed-stage, or so-called micro VC, funds, they were cool to the idea. In fact, it took Kim — formerly a partner with the venture firm Rustic Canyon Ventures — roughly two years to raise the firm’s $28.5 million debut fund.

Fast-forward, and Kim’s Cendana Capital — which has backed venture firms Forerunner Ventures, SoftTech VC, IA Ventures, Freestyle Capital, K9 Ventures, Bowery Capital and Lerer Hippeau Ventures, among others  — just closed on $260 million in fresh capital across a network of five funds.

One vehicle is Cendana’s third and newest fund-of-funds, which works just like that $28.5 million debut fund, except it’s nearly three times as big, with $80 million in commitments.

Kim also raised $35 million to make direct co-investments; a $60 million co-investment fund that he manages on behalf of The University of Texas Investment Management Company; a $75 million fund called Cendana Blackbird that Cendana manages on behalf of an unnamed pension fund (it invests in Cendana’s portfolio funds in cases where it can get a greater allocation); and a $10 million, late-stage fund called Cendana Kendall that’s being managed on behalf of an unnamed family office. (The idea is for Kim to plug the money into one or two breakaway companies in one of his fund managers’ portfolios.)

Altogether, the San Francisco-based outfit now manages around $450 million — which says a lot about how much the market has changed. We talked yesterday with Kim — who runs Cendana with principal Graham Pingree — about that ongoing evolution.

TC: Cendana seems to be an investor in every major micro VC fund out there. How many funds are you involved with?

MK: We have 15 “core” relations, where we’ve invested $8 million to $10 million, then we have a pilot program where we invest $1 million in 8 or 9 groups that we like but we have some lingering questions about their strategy. For example, NextView Ventures in Boston and Mucker Capital in L.A. were part of our pilot program because we didn’t have a high conviction about either the Boston or L.A. ecosystems. Now we do, so they’ve become core.

The hardware investment firms Bolt and Root Ventures also became part of that pilot program, because we had questions about whether seed was the right entry point for hardware investing.

TC: Which is the newest fund to join your pilot portfolio?

MK: Notation Capital in Brooklyn.

TC: Do all “pilots” become “core”?

MK: No. And we’ve ended up not continuing with some core funds as some have evolved from seed-stage to Series A-stage funds, and backing them is not the mandate our LPs gave us, notwithstanding how amazingly they’ve performed for us. I won’t share publicly which those are, though.

TC: Where do you draw the line? So many of your managers are now investing two or three times the amount of their debut funds.

MK: We’re SoftTech’s biggest LP. And SoftTech could have easily raised a $150 million vehicle (when it was last out fundraising). But it realized a seed found should be no larger than $100 million so raised a $100 million seed fund and a separate $50 million opportunity fund. We’re investors in the $100 million piece alone.

TC: So as far as you’re concerned, a fund can’t do seed well with more than $100 million under management. What about ownership stakes? Do you have a strong feeling about how much a manager should own of each company? 

MK: We look for those who lead deals. We think ownership is paramount. We want our fund managers to focus on at least 15 percent ownership. So with the average seed fund going from $1 million to $3 million in recent years, to lead that round, you need to write a check for $1.5 million. That’s why these seed funds have gotten bigger.

 TC: Do you care how many people are managing money at these seed firms? You see some that have several partners; you have others, like K9 Ventures, that’s run by a solo general partner, Manu Kumar.

MK: We look at it as capital per partner. Lerer Hippeau has four people investing $113 million, so that’s $28 million per partner. We think the ideal range is $25 million to $35 million per partner.

TC: There are so many seed fund investors. How many groups do you think you’ve met with altogether, and do you ever fund firms outside of the U.S.?

MK: Since inception, we’ve talked with around 700 firms, either in person or over the phone.

We haven’t invested internationally. We felt that the ecosystems outside the U.S. were substantially weaker, owing to the lack of available follow-on capital. That was a huge concern in Europe, where for a long time it was basically Accel and Balderton and Index.  But now there’s BlueYard Capital in Berlin and Felix Capital and Mosaic Ventures in London. There’s a lot more going on, so we think the ecosystem has gotten better.

TC: You make direct investments in certain companies when you can. For example, you were able to get equity in Dollar Shave Club through Forerunner Ventures, which also provided an introduction to the company when you asked for one. How do these things come together? How do you choose which companies to pursue with so many startups in your managers’ portfolios?

MK: We have a monthly call with fund managers, but we’re also always trading calls or IMing because we have a pretty close relationship with them. And if a fund manager talks about a certain company and keeps mentioning it every month and it becomes clear that it’s tracking well, we’ll ask for an intro to its management team.

TC: Does that ever create a conflict for your fund managers?

MK: We only invest if the fund manager is coming into the same round, and usually they are stretching their reserves to do that; they can’t do full pro rata, which creates an opportunity for us to try and get in.

These are usually very attractive opportunities; we’ve had to fight to get into most of these. But I do think the opportunity set is increasing as these companies bubble up to the Series A and B stages.

TC: Any thoughts on secondary sales and whether seed funds should hang on for the long haul if they have a buzzy company in their portfolio?

MK: There’s definitely an opportunity for managers to sell into these higher-priced rounds. Our advice is if you have a 10x return, consider selling 10 to 20 percent and getting liquidity to investors. And we’ve seen a lot more of that over the last 12 to 24 months.

Seed funds can become hostages in high-valuation companies otherwise. Say the company ends up raising $100 million at a $2 billion valuation. Well, the seed would have been happy to sell, but now the new investor wants 3x from there, so this company has to get to a $6 billion valuation, and a lot of bad things can happen in pursuit of that.

TC: Do you sell before the big exit? I’m guessing you don’t need to worry about so-called signaling risk — or do you?

MK: We really don’t. We could sell into the next round and no one would blink an eye. It’s a negative signal if Sequoia does it. If Cendana does it, no one cares.

Amazon will refund millions of unauthorized in-app purchases made by kids

Amazon will refund millions of unauthorized in-app purchases kids made on mobile devices, having now dropped its appeal of last year’s ruling by a federal judge who sided with the Federal Trade Commission in the agency’s lawsuit against Amazon. The FTC’s original complaint said that Amazon should be liable for millions of dollars it charged customers, because of the way its Appstore software was designed – that is, it allowed kids to spend unlimited amounts of money in games and other apps without requiring parental consent.

The FTC had previously settled with both Apple and Google on similar charges, before turning its sights to Amazon.

The issue had to do with the way the Amazon Appstore’s in-app purchasing system worked. The Amazon Appstore is the store that comes preloaded on Amazon mobile devices, like Kindle Fire tablets, for example, though there is a way to load it onto other Android devices, too.

Of course, many kids’ game developers notoriously try to blur the lines between what’s free and paid. They also often design games in a way that they only fully function when kids use in-game items, which can be sometimes earned through gameplay or other times purchased through the app itself. Kids are pushed to buy these things regularly – as any parent can tell you, having experienced their kids’ begging for these items.

But in Amazon’s Appstore, which launched back in 2011, the company didn’t originally require passwords on in-app purchases. This allowed kids to buy coins and other items to their hearts’ content. One particularly awful example involved a game called “Ice Age Village” that offered an in-app purchase of $99.99.

Amazon introduced password-protected in-app purchases in March 2012, but then only on those where the purchase exceeded $20. In early 2013, it updated the system again to require passwords, but also allowed a 15-minute window afterwards where no password was required. The FTC said Amazon didn’t obtain “informed consent” until July 2014.

 To make matters worse, parents complaining weren’t told how to get a refund and Amazon had even suggested at times that refunds weren’t possible, the FTC’s complaint had said.

Amazon and the FTC have now agreed to end appeals related to the earlier ruling, the FTC announced on Tuesday, April 4. Another issue that had come into play was the FTC’s request for an injunction to forbid Amazon from similar conduct in the future. The court denied that injunction, the FTC appealed, and Amazon cross-appealed the ruling that said Amazon had violated the law.

Now the two parties have agreed to end their litigation and begin the refund process.

More than $70 million in in-app charges made between November 2011 and May 2016 may be eligible for refunds, the FTC notes. It’s not likely that all affected customers will take the time to make their requests, however.

Amazon has not yet announced how the refund program will operate or when it launches but these details are to come shortly, says the FTC.

PS4 System Software Update 4.50 Breaks Wi-Fi for Some Players

Sony’s last big update for the PlayStation 4 – firmware v4.50 – seems to have broken Wi-Fi for some users, it seems.

The day the sytem software update arrived, a new thread over on PlayStation Forums complained about being unable to connect their console to the network with existing settings. Instead, the PS4 threw up an error code NW-31297-2, which states that it “could not connect to the Wi-Fi network because the Wi-Fi password is not correctly set on the PS4, or the wireless network is busy”.

PS4 System Software Update 4.50 Breaks Wi-Fi for Some Players

In their post, the user said that “[I am] pretty sure the password is correct”, and the Wi-Fi was working just fine on every other device.

Since then, over 250 replies have been posted to the thread, with most people running into the same problem after updating to firmware v4.50. Some have been forced as far to buy a Wi-Fi extender (with an in-built Ethernet port), just so they could restore connectivity to their PS4.

Clearly, everyone in the thread isn’t happy about this new issue, and it hasn’t helped that Sony was initially unresponsive. The company has issued a separate statement since: “We are aware and are looking into the situation.”

Until then, you’ll just have to run an Ethernet cable between your router and the PS4. And if that’s not possible, be forced to play offline. In an age where so many games demand an always-online connection, that’s not good at all.

In other PS4-related news, PlayStation Now – the video game streaming service for Windows PCs – is set to get PS4 titles soon.

Alibaba invests in WayRay, a maker of augmented-reality dashboards for smart cars

After launching its first car last year, Alibaba is digging deeper into the automobile industry. The Chinese Internet and e-commerce behemoth is the lead investor in smart car tech developer WayRay’s $18 million Series B round, the startup announced.

Founded in 2012, WayRay makes holographic navigation systems. According to its funding announcement, WayRay has already spent $10 million of its own capital, as well as previous venture funding, on the technology that underpins Navion, an augmented-reality dashboard that overlays directions and other information onto a driver’s view of the road. The company plans to launch a consumer version of Navion in 2017.

In a prepared statement, Alibaba Group’s senior investment director, Ethan Xie, said, “We believe there is huge potential in the development of leading-edge technology like augmented reality and its application to various industries, like WayRay’s AR navigation system in the auto sector. The potential of augmented reality makes it an exciting and promising area.”

Alibaba made its debut in the car industry last summer, when the RX5, a smart car it developed with SAIC (one of China’s “big four” state-owned auto manufacturers—opened for pre-orders. The RX5 uses Alibaba’s Yun operating system and the company hopes to make the vehicle part of an Internet-of-Things ecosystem that will include its other smart hardware and Internet services like Alipay.

 But Alibaba’s smart cars are already up against rivals from other big Chinese tech companies like LeEco, which bills its electric car LeSee as “the first mobility ecosystem on wheels,” and Baidu, which is developing smart car technology and autonomous vehicles with BAIC, another of China’s big four state-owned automakers.

WayRay also said that it will partner with Banma Technologies—a joint venture between Alibaba Group and SAIC—to create an augmented-reality navigation and entertainment system for a car that will be launched by Banma in 2018. WayRay claims that this is “the world’s first vehicle in-production with a holographic AR head-up display.”

Makeblock raises $30 million for robot-building kits for kids

Remember when kids could simply play with their toys? They still can. But parents are increasingly spending on toys that are chockablock with tech components, and that promise to turn their kids into software developers or robotics engineers. The Toy Industry Association, which held its International Toy Fair in New York last month, has even identified robotics-education as a major trend for the market in 2017.

Now, a Shenzhen-based startup called Makeblock has raised $30 million in Series B venture funding to serve all those parents with programmable robots, and robot-building kits for kids and teens. Makeblock claims it has customers in 140 countries and products being used by educators in 20,000 different schools worldwide today.

The startup’s best-known products include programmable rovers in the mBot series, and the Airblock, a modular toy drone that even beginners can assemble. But the company offers a very wide variety of techie toys, including some that are more whimsical. For example, its Music Robot Kit includes a xylophone, and a motorized hammer. If built and programmed successfully, it can play a certain score, or users can bang out notes from a remote PC keyboard.

Makeblock uses a graphical programming environment to turn code “writing” into something of a game. Beginners never have to write and edit code to issue commands to their robots. They just have to place game pieces on a screen in a certain order.

Evolution Media China and Shenzhen Capital Group led the investment in Makeblock. The capital should help the startup compete against a wide variety of tech toy makers that sell kits and apps which teach kids some programming fundamentals. Competitors include LittleBits, SparkFun, ArcBotics, Flybrix and even the makers of robots that are programmable out of the box like Wonder Workshop and Ozobot.

 Makeblock CEO Jasen Wang said he grew up in a village without a lot of money or technology. He personally only touched a computer himself for the first time in college, learning to code relatively late in life. But his passion for technology made him want to bring more young students into the maker movement, which is why he started Makeblock in 2011.

The company plans to use its funding for hiring, new product development, manufacturing and international expansion. Among other things, it plans to open an office in the US. Investors see the possibility for the birth of a “next-generation Lego” in Makeblock, the CEO said.

To boot, mergers and acquisitions have been robust in the “juvenile products” industry in recent years, with toy companies often acquiring teams or businesses to move in markets where they are not already expert. In other words, the prospects for an exit look good even for companies that may not hold out for an IPO on a major exchange.

Simple Ways To Make Your Organization More Successful This Year

If you want 2017 to be your organization’s most successful ever, you can begin the company optimization process immediately. While there are numerous strategies you might use to attain great results like enhanced conversion and more industry influence, the following techniques can be particularly powerful:

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  1. Focus On Employee Growth.

If you’re serious about making your organization increasingly successful this year, you need to focus on employee growth. The more skilled and knowledgeable your staff is, the more likely you are to attract new clients and ensure that daily tasks are completed quickly and correctly. One great way to make employee growth a reality is to attain assistance from a team of skilled business consultants. Companies like KEYGroup Consulting are pleased to offer clients numerous resources and tools, including the 360 degree employee survey.

  1. Implement Social Media Optimization (SMO) Services.

In addition to focusing on employee growth, make sure that you start implementing social media optimization services. These services are effective because they help make your brand increasingly visible on popular social channels such as:






There are several SMO strategies that a digital marketing firm might employ to help you connect and convert prospective clients on some or all of the aforementioned channels. One technique might be a Twitter poll. These polls enable digital experts to conduct research which provides them with a better understanding of your target audience’s needs and wants. When you start looking for an SMO company, try to locate a team of experts that can offer several other digital marketing services. By attaining additional services such as search engine optimization and web design and development, you can increase the likelihood of maintaining the type of dynamic online presence that sends your conversion rates through the ceiling.

  1. Utilize Customer Relationship Management (CRM) Strategies.

In addition to attaining great SMO services, make sure that you start implementing CRM strategies. These strategies are important because they help optimize your engagement of prospective clients and current customers. For example, CRM software enables your sales team to keep detailed records of each conversation they have with a client while also viewing every recent purchase they make. This knowledge will empower them to communicate in an informed manner while also enabling them to determine which products they should push while talking to the customer.

Start Focusing Now!

Business growth doesn’t happen magically or sporadically. Rather, it takes place when corporate leaders implement strategies that are known to generate results. Use some or all of the strategies outlined above to keep your company on the road to extraordinary growth this year!

Did Snap leave money on the table?

Snap priced its IPO at $17 per share on Wednesday, raising $3.4 billion. Then it opened Thursday at $24 per share and closed at $24.48. That’s a 44 percent gain for the select investors who bought into the IPO.

And that gain looks great… for new investors. But it also means that Snap could have sold its shares for a higher price!

If Snap priced its shares just a little higher at, say, $19 per share, they would have raised $3.8 billion, or $400 million more than the $3.4 billion they actually raised. And they still would have generated favorable publicity from the new investor gains of 29 percent.

So what happened? Snap originally proposed its IPO price range of $14 to $16 per share and then went above it, settling on $17 per share after strong appetite on the investor roadshow.

But what they clearly didn’t anticipate was the demand from the “retail investors.” You can probably blame the investment bankers on this one. It’s their job to help the company assess how it will do in the public markets.

 They usually recommend some sort of first-day “pop,” the term for shares going up on the first day of trading. This is basically just to make a good first impression on the public. However, the banks often aim for closer to 20 percent than 40 percent.

So if Snap had $400 million more to play with, what would they do with it? They could use it for more hiring, acquisitions, research and development…

A Comparative Review ofHGH and Its Supplements

It must be known to you that Human Growth Hormone (HGH) has high potential to enhance the growth of bones and muscles of the body. Due to its effects on the body, it is often used by the bodybuilders and athletes to increase their muscle mass and give their body a chiseled look. Although it was first developed as a medication for treating growth deficiency disorders, it is also used as sports nutrition nowadays.

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What are HGH supplements and how is it different from HGH itself?

There are several diet supplements consisting of HGH hormone. These supplements produce the same results as that of the hormone itself. To look into the function of these supplements, we must first focus on HGH alone.

HGH is synthesized in the pituitary gland of the brain. In normal cases, the pituitary gland synthesizes adequate amount of the hormone. However, in the case of a deficiency of this particular hormone, synthetic forms of the hormone are used to treat them.

However, the HGH supplements are actually different from the synthetic HGH. These supplements do not serve as an alternative to HGH; it rather acts as an enhancer or a booster to provide nutritional support to the pituitary gland. The master regulator requires these nutritional factors for the proper secretion of several hormones. Once it gets the raw material for its function, it profusely produces and secretes required amount of growth hormones depending upon the required stimulus.

Factors determining the effect of HGH supplements

It has been found that the injectable forms of the HGH hormones produce the same effect on the body as that of the endogenous hormone. However, these nutritional supplements produce effects which depend on a variety of factors- the strength of the dosage, frequency of dose recommended by the physician, and weight, age and overall health of the person administering such supplements.

Only going for HGH injection to boost the growth of the body by bodybuilders and athletes is often discouraged. This is because boosting a normal functioning pituitary gland might lead to adverse side effects. Therefore, it is better to combine such administration with a fad diet plan. This maximizes the effect of such supplements in the body. Such a combination is also known as an HGH diet plan.

Reasons for not supporting an HGH diet plan

HGH diets are often recommended by athletes to optimize the process of weight loss and long-term management. It also helps to increase endurance and stamina, to build muscle. Such techniques help to distribute the focus on diet as well as exercise keeping in mind the type and duration of exercise leading to a healthy lifestyle.

However, it is better to avoid such HGH diet recommendations from those who seek a drastic decrease in weight without putting as much effort in the process as it is required. You will never find any possible combination of supplements that can produce such effects. Moreover, such combinations can lead to severe health problems in the future.

To conclude, it is better to know all the attributes related to HGH supplements which can produce almost the same results as that of the growth hormone itself. If you want to experience such changes in your body, it is best to consult a physician before taking the drug.